[HTML][HTML] Benzamide derivative radiotracers targeting melanin for melanoma imaging and therapy: Preclinical/clinical development and combination with other …

J Rouanet, M Quintana, P Auzeloux, F Cachin… - Pharmacology & …, 2021 - Elsevier
… richly pigmented tissues, leading to the first radiotracer N-(2-diethylaminoethyl)-4-iodobenzamide
(BZA), specifically designed to diagnose malignant melanoma (Michelot et al., 1991). …

[HTML][HTML] Theranostic approach for metastatic pigmented melanoma using ICF15002, a multimodal radiotracer for both PET imaging and targeted radionuclide therapy

L Rbah-Vidal, A Vidal, EMF Billaud, S Besse… - Neoplasia, 2017 - Elsevier
… on the human eyes except in the case of ocular melanoma, whereas great uveal uptake
was … melanoma and metastases with iodine-123-N-(2-diethylaminoethyl 4-iodobenzamide) …

[HTML][HTML] Phase I study of [131I] ICF01012, a targeted radionuclide therapy, in metastatic melanoma: MELRIV-1 protocol

E Thivat, J Rouanet, P Auzeloux, N Sas, E Jouberton… - BMC cancer, 2022 - Springer
… approach for SPECT imaging of metastatic melanoma leading … Patients with cutaneous
melanomas will be recruited at the … -Ferrand and patients with uveal melanomas will be recruited …

PET and SPECT imaging of melanoma: the state of the art

W Wei, EB Ehlerding, X Lan, Q Luo, W Cai - European journal of nuclear …, 2018 - Springer
… Interestingly, recent research has proposed that N-(2-diethylaminoethyl) rather than the
aromatic … Ga-TRAP(RGD) 3 showed high-contrast visualization of the M21 tumor. e Chemical …

Imaging malignant melanoma with 18F-5-FPN

H Feng, X Xia, C Li, Y Song, C Qin, Q Liu… - European journal of …, 2016 - Springer
… The higher sensitivity of PET and SPECT in many … The kidneys and bladder were visualized
in all animals, demonstrating … -[2-diethylamino-ethyl]4-iodobenzamide) (iodoBZA) labelled …

MC1R and melanin-based molecular probes for theranostic of melanoma and beyond

H Shi, Z Cheng - Acta Pharmacologica Sinica, 2022 - nature.com
… in two melanoma patients for visualization of metastases … have been developed for melanoma
SPECT and PET imaging. … The N-(2-diethylaminoethyl)-4-iodobenzamide (BZA) was first …

N-(2-(dimethylamino) ethyl)-4-18F-fluorobenzamide: A novel molecular probe for high-contrast PET imaging of malignant melanoma

A Pyo, HS Kim, HS Kim, M Yun, DY Kim… - Journal of Nuclear …, 2019 - Soc Nuclear Med
melanoma detection using SPECT (16–19). These probes were evaluated in B16 murine
melanoma… -DMFB to visualize LNs harboring metastatic malignant melanoma in mouse models…

[HTML][HTML] Translating molecules into imaging—the development of new PET tracers for patients with melanoma

L Vercellino, D de Jong, L Dercle, B Hosten… - Diagnostics, 2022 - mdpi.com
… a murine model of melanoma after administration of N-(2-diethylaminoethyl)-4-iodobenzamide
( 125 I… metastasis in 87 patients with a history of cutaneous or ocular melanoma. While the …

Imaging Sigma-1 Receptor (S1R) Expression Using Iodine-124-Labeled 1-(4-Iodophenyl)-3-(2-adamantyl)guanidine ([124I]IPAG)

KK Gangangari, A Váradi, S Majumdar… - Molecular imaging and …, 2020 - Springer
… The tumor to background increases with time, and tumors could be clearly visualized starting
from 24 h post administration. Similar results were obtained in mice bearing LNCaP tumors. …

Development of Radiofluorinated Nicotinamide/Picolinamide Derivatives as Diagnostic Probes for the Detection of Melanoma

YH Lo, TY Chang, CL Chen, MH Lin, HE Wang… - International Journal of …, 2021 - mdpi.com
… B16 melanoma (6.75 %ID/g) and liver (6.04 %ID/g) at 1 h after intravenous injection [6]. The
first clinical trial of 123 IN-(2-diethylaminoethyl)4-Iodobenzamide ( … to ocular melanoma, eye